Pedigree analysis of Hungarian Rett syndrome girls.

Twenty-two Hungarian families with Rett syndrome girls were genealogically examined. None of our 23 probands was born to first-cousin couples, but we established increased number of consanguineous marriages among the ancestors of the patients. Observing the places where the Rett families originate from, we found a predominance in the north-east part of Hungary. Our results support the findings of the Swedish analysis.