Current drug safety · 2021
A Case of Quinacrine-induced Psychosis: Case Report.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
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Pedapudi Anangamanjari, Stewart Jonathan, Patel Ankita
Аннотация
BACKGROUND: Quinacrine is an older antimalarial drug that remains in use for a variety of illnesses including treatment-resistant giardiasis.
CASE PRESENTATION: We report a patient with no prior psychiatric history who developed mild, prodromal psychiatric symptoms when treated with quinacrine for treatment-resistant giardiasis. Symptoms resolved when the drug was stopped, recurred with greater severity (requiring involuntary psychiatric hospitalization) when restarted and promptly resolved again when the drug was finally stopped.
CONCLUSION: Although quinacrine remains in use today, providers may be unaware of its potential for serious neuropsychiatric toxicity.
CASE PRESENTATION: We report a patient with no prior psychiatric history who developed mild, prodromal psychiatric symptoms when treated with quinacrine for treatment-resistant giardiasis. Symptoms resolved when the drug was stopped, recurred with greater severity (requiring involuntary psychiatric hospitalization) when restarted and promptly resolved again when the drug was finally stopped.
CONCLUSION: Although quinacrine remains in use today, providers may be unaware of its potential for serious neuropsychiatric toxicity.