Mucinous adenocarcinoma of the base of the tongue: A case report.

A 50-year-old male patient presented with a nodular lesion at the right base of the tongue. An incisional biopsy was performed, and the histopathological evaluation revealed an ill-defined multicystic papillary proliferation of mucin-producing cells. Immunohistochemically, tumor cells were positive for CK7 and negative for CK20, p40, p63, SOX10, SMA, and calponin. The Ki67 proliferation index accounted for about 27%. Based on the diagnosis of papillary-type salivary gland mucinous adenocarcinoma (MAd), the patient underwent surgical excision. During a 7-month follow-up period, no recurrence or metastasis was observed. We also conducted a literature review of 56 cases of MAd published in the English language, summarizing the clinical, demographic, histopathological, and prognostic features of the tumor.