Медицинская библиотека · Head & neck · 2021

Increased body mass index predicts prolonged survival in patients with head and neck squamous cell carcinoma.

Wu Eric L, Peesay Tejasvi, Randall James A, Nelson Lacey L, Shearer Sarah C, Johnson Bria C, Maxwell Jessica H

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Аннотация

BACKGROUND

Higher body mass index (BMI) may have a protective effect on survival in patients with head and neck cancer. The aim of this study was to determine the effect of BMI on overall survival (OS) in veterans with head and neck squamous cell carcinoma (HNSCC).

METHODS

A cohort of 702 patients diagnosed with HNSCC between 1995 and 2019 were identified at the Washington DC Veterans Affairs Medical Center, and 342 patients were included for analysis. Records were queried for clinical-demographic data, BMI, and outcomes.

RESULTS

HNSCC patients categorized as overweight or obese at time of diagnosis had a lower 3-year risk of death (p = 0.033) and improved OS (p < 0.001) compared to patients who were underweight or normal weight. The majority of locoregional recurrences occurred in patients with low or normal pretreatment BMI.

CONCLUSIONS

Higher BMI at diagnosis may have a protective effect on OS in veterans with HNSCC.

Для цитирования: Wu Eric L, Peesay Tejasvi, Randall James A, Nelson Lacey L, Shearer Sarah C, Johnson Bria C, Maxwell Jessica H. Increased body mass index predicts prolonged survival in patients with head and neck squamous cell carcinoma.. Head & neck. 2021. DOI: 10.1002/hed.26922.

Предметные рубрики MeSH

Body Mass Index Head and Neck Neoplasms Humans Neoplasm Recurrence, Local Obesity Prognosis Squamous Cell Carcinoma of Head and Neck

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