Effect of Pre-Orthodontic CGF-Assisted GTR for Class II Furcation Lesions After Orthodontic Treatment: 5-Year Observation.

AIMS: The purpose of this case series is to discuss the effect of orthodontic treatment (OT) on the regenerative surgery of furcation defects.

MATERIAL AND

METHODS

This was a consecutive case series with a 5-year follow-up. Eight patients of stage III periodontitis with 10 mandibular Class II buccal furcation defects were included. The furcation defects were treated by guided tissue regeneration combined with bone graft and concentrated growth factors. OT was started at 1-year post-surgery. Clinical examination and CBCT were performed at baseline, 12 months post-surgery, and 5 years post-surgery.

RESULTS

The mean clinical attachment loss and probing depth improved from baseline to different time points post-surgery. And there were no significant changes at subsequent time points post-surgery (P > .05). A statistically significant reduction in the mean horizontal, vertical bone loss, and volume of furcation defects from baseline to different time points post-surgery has been shown (P < .001). No statistically significant difference was observed between 1-year and 5 years post-surgery (P > .05).

CONCLUSIONS

In summary, the combined regenerative therapy showed good results in the treatment of furcation defects. Moreover, the combined regenerative therapy was shown to be maintained throughout and following orthodontic treatment.