[The relationship among human, gorilla, chimpanzee and orangutan].

The phylogeny of hominoid is still an open question. The contrary point is which relationship is more closed related between human and gorilla and human and chimpanzee. Tyrosinase is the essential enzyme in melanogenesis. The mutation of tyrosinase gene causes albinism. The five exons of tyrosinase gene were sequenced for gorilla, chimpanzee, orangutan and gibbon in hominoid. Combined with the human tyrosinase gene sequence, the gene tree was constructed using parsimony method. The results show that the relationship between human and gorilla is more closed related than between human and chimpanzee.