Journal of cardiovascular medicine (Hagerstown, Md.) · 2024
Prognostic significance of electrophysiological study in drug-induced type-1 Brugada syndrome: a brief systematic review.
Систематический обзорСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Mascia Giuseppe, Brugada Josep, Barca Luca, Benenati Stefano, Della Bona Roberta, Scarà Antonio, Russo Vincenzo, Arbelo Elena, Di Donna Paolo, Porto Italo
Аннотация
BACKGROUND: Risk stratification in drug-induced type-1 Brugada syndrome (BrS) patients is challenging. The role of electrophysiological study (EPS) is debated as the majority of drug-induced type-1 BrS patients would not be studied according to the latest recommendations.
METHODS: A complete systematic literature search was performed to gauge the EPS role in this population. Three subgroups were defined: positive-EPS group, negative-EPS group, no-EPS group.
RESULTS: Among 1318 drug-induced type-1 BrS patients, no significant difference in the incidence rate of arrhythmic events was observed between groups (I2 = 45%, P for subgroup difference = 0.10) during a mean follow-up of 5.1 years, also considering symptomatic status.
CONCLUSION: In long-term follow-up of drug-induced type-1 BrS patients, EPS does not seem to aid prognostic stratification.
METHODS: A complete systematic literature search was performed to gauge the EPS role in this population. Three subgroups were defined: positive-EPS group, negative-EPS group, no-EPS group.
RESULTS: Among 1318 drug-induced type-1 BrS patients, no significant difference in the incidence rate of arrhythmic events was observed between groups (I2 = 45%, P for subgroup difference = 0.10) during a mean follow-up of 5.1 years, also considering symptomatic status.
CONCLUSION: In long-term follow-up of drug-induced type-1 BrS patients, EPS does not seem to aid prognostic stratification.