Feasibility of controlling or eradicating the hepatitis B virus.

A hepatitis B vaccine, prepared from the hepatitis B surface antigen in human blood has been available since the early 1980s. A recombinant vaccine, which can be supplied in unlimited amounts, was recently introduced. Based on current data, these vaccines are highly effective and safe. The most effective procedures for controlling hepatitis B virus is the vaccination of newborn infants. After universal vaccination of newborns has been ensured, vaccination of susceptible persons in older age groups could be instituted. Any attempt at eradicating hepatitis B virus will require international cooperation, and ideally the hepatitis B virus vaccine should be integrated into other childhood vaccination programs.