Expedient synthesis of poly-aryl substituted allenylsilanes via silylation of 1,3-diaryl propargyl carbonates.

Allenylsilanes serve as important and versatile intermediates in organic synthesis, finding widespread applications in medicinal chemistry and materials science. A mild and regioselective silylation of 1,3-diaryl propargyl carbonates using palladium and copper as co-catalysts is reported herein. Under this method various poly-aryl substituted allenylsilanes were obtained in mono-regioselectivities and excellent yields. Compared with the existing single-metal catalytic systems, this Pd/Cu cooperative activation mode exhibits superior substrate adaptability and reaction efficiency. This work not only enriches the synthetic methodology for allenylsilanes but also provides a new avenue for the synthesis of poly-aryl substituted allene derivatives.