American journal of ophthalmology · 2007
Autologous plasmin-assisted vitrectomy for stage 5 retinopathy of prematurity: a preliminary trial.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Tsukahara Yasutomo, Honda Shigeru, Imai Hisanori, Kondo Naoshi, Fujii Shigeki, Yokoyama Naoki, Hirata Akira, Kawaji Takahiro, Fukushima Mikiko, Tanihara Hidenobu, Negi Akira
Аннотация
PURPOSE: To evaluate the efficacy of autologous plasmin (AP)-assisted vitrectomy for stage 5 retinopathy of prematurity (ROP).
DESIGN: Interventional case series.
METHODS: Six consecutive eyes of four children with stage 5 ROP were treated. The patients' ages at the surgery ranged from five to eight months after birth. Four eyes showed closed-closed configuration and two eyes showed open-open configuration. After lensectomy and dissection of the anterior proliferative membrane, 0.03 to 0.22 International Unit (IU) of AP was administrated into the vitreous cavity. After 15 to 30 minutes of incubation, the proliferative membrane was treated.
RESULTS: The proliferative membrane was removed successfully without iatrogenic retinal break. Complete reattachment of the posterior pole retina was achieved in all six eyes (100%). No obvious complication was observed in the follow-up period, which ranged from 11 to 14 months.
CONCLUSIONS: These results suggest the benefit of AP in the vitrectomy for treatment of stage 5 ROP.
DESIGN: Interventional case series.
METHODS: Six consecutive eyes of four children with stage 5 ROP were treated. The patients' ages at the surgery ranged from five to eight months after birth. Four eyes showed closed-closed configuration and two eyes showed open-open configuration. After lensectomy and dissection of the anterior proliferative membrane, 0.03 to 0.22 International Unit (IU) of AP was administrated into the vitreous cavity. After 15 to 30 minutes of incubation, the proliferative membrane was treated.
RESULTS: The proliferative membrane was removed successfully without iatrogenic retinal break. Complete reattachment of the posterior pole retina was achieved in all six eyes (100%). No obvious complication was observed in the follow-up period, which ranged from 11 to 14 months.
CONCLUSIONS: These results suggest the benefit of AP in the vitrectomy for treatment of stage 5 ROP.