Journal of glaucoma · 2006
Frequency doubling technology perimetry with the Humphrey Matrix 30-2 test.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Brusini Paolo, Salvetat Maria Letizia, Zeppieri Marco, Parisi Lucia
Аннотация
PURPOSE: To assess the Humphrey Matrix 30-2 test in detecting functional glaucomatous damage.
PATIENTS AND METHODS: One eye in each of 60 healthy individuals, 108 patients with ocular hypertension (OHT), and 150 patients with preperimetric (48) or perimetric (102) high-tension primary open-angle glaucoma (POAG) were considered. Visual fields were assessed by the standard automated perimetry (SAP) Humphrey Field Analyzer 30-2, frequency doubling technology (FDT) N-30, and Humphrey Matrix 30-2 tests. Significantly abnormal points in the pattern deviation probability plot, testing time, sensitivity, specificity, and area under the receiver operating characteristic curve of the FDT tests were evaluated.
RESULTS: FDT revealed a significantly greater percentage of depressed points than did SAP in OHT and preperimetric POAG eyes. The FDT-N-30 test showed a significantly greater percentage of areas with P < 5% in the OHT, preperimetric POAG, and early POAG groups. The Matrix-30-2 test provided an area under the receiver operating characteristic curve slightly lower than the FDT-N-30 test in the preperimetric POAG group, and significantly greater in the perimetric POAG group.
CONCLUSIONS: FDT perimetry appeared more sensitive than SAP in detecting early glaucomatous VF loss. The FDT-N-30 test showed a slightly higher ability to detect early glaucomatous damage in patients at risk for the development of glaucoma, whereas the Matrix-30-2 test provided a more detailed characterization of the glaucomatous VF loss pattern, although it required 30% more time.
PATIENTS AND METHODS: One eye in each of 60 healthy individuals, 108 patients with ocular hypertension (OHT), and 150 patients with preperimetric (48) or perimetric (102) high-tension primary open-angle glaucoma (POAG) were considered. Visual fields were assessed by the standard automated perimetry (SAP) Humphrey Field Analyzer 30-2, frequency doubling technology (FDT) N-30, and Humphrey Matrix 30-2 tests. Significantly abnormal points in the pattern deviation probability plot, testing time, sensitivity, specificity, and area under the receiver operating characteristic curve of the FDT tests were evaluated.
RESULTS: FDT revealed a significantly greater percentage of depressed points than did SAP in OHT and preperimetric POAG eyes. The FDT-N-30 test showed a significantly greater percentage of areas with P < 5% in the OHT, preperimetric POAG, and early POAG groups. The Matrix-30-2 test provided an area under the receiver operating characteristic curve slightly lower than the FDT-N-30 test in the preperimetric POAG group, and significantly greater in the perimetric POAG group.
CONCLUSIONS: FDT perimetry appeared more sensitive than SAP in detecting early glaucomatous VF loss. The FDT-N-30 test showed a slightly higher ability to detect early glaucomatous damage in patients at risk for the development of glaucoma, whereas the Matrix-30-2 test provided a more detailed characterization of the glaucomatous VF loss pattern, although it required 30% more time.