Journal of pharmacy & bioallied sciences · 2024
Efficacy of Various Herbal Preparations Against Oral Candida: A Lab-Based Study.
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Karni Prashant A, Muraleedharan Aparna, Bhandary Srikala, Mujoo Sheetal, Maini Anuj Paul, Chaturvedi Mudita
Аннотация
AIM: This research was done to analyze the effectiveness related to herbal chemicals in tackling candidiasis.
MATERIALS AND METHODS: Grounded and ethanol-extracted residues of plants like Avicennia marina, Fagonia indica, Portulaca oleracea, Lawsania inermis, Ziziphus spina, Asphodelus tenuifolius, and Salvadora persica were used in the study. The extract was used against candida species, after which the antibacterial as well as cytotoxicity toward the former were evaluated.
RESULTS: L. inermis and P. oleracea with minimal inhibitory concentration of approx. 10 cenmL had an increased activity against candida species. The preparations of these plants acted against Candida albicans during its stages related to pathogenesis during biofilm production. Superadded infections like in case of bacterial infections along with candida can be difficult to cure. On human RBCs, these plant preparations had no toxicity at their minimum inhibitory concentration level.
CONCLUSION: We concluded that, as far as being anti-candida and acting against MDR bacterial infections, preparations of plants were effective as an alternative to allopathic drugs.
MATERIALS AND METHODS: Grounded and ethanol-extracted residues of plants like Avicennia marina, Fagonia indica, Portulaca oleracea, Lawsania inermis, Ziziphus spina, Asphodelus tenuifolius, and Salvadora persica were used in the study. The extract was used against candida species, after which the antibacterial as well as cytotoxicity toward the former were evaluated.
RESULTS: L. inermis and P. oleracea with minimal inhibitory concentration of approx. 10 cenmL had an increased activity against candida species. The preparations of these plants acted against Candida albicans during its stages related to pathogenesis during biofilm production. Superadded infections like in case of bacterial infections along with candida can be difficult to cure. On human RBCs, these plant preparations had no toxicity at their minimum inhibitory concentration level.
CONCLUSION: We concluded that, as far as being anti-candida and acting against MDR bacterial infections, preparations of plants were effective as an alternative to allopathic drugs.