International journal of fertility & sterility · 2011
Evaluation of homocysteine levels in patients with polycystic ovarian syndrome.
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Salehpour Saghar, Manzor-Al-Ajdad Ozra, Samani Elham Neisani, Abadi Alireza
Аннотация
BACKGROUND: To determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls.
MATERIALS AND METHODS: In this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed.
RESULTS: The mean level of homocysteine was 16.25 ± 11.94 μmol/L in patients with PCOS and 11.58 ± 3.82 μmol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for hyperhomocysteinemia compared with BMI-matched control women.
CONCLUSION: These data suggest that homocysteine levels are elevated in the PCOS population. Further studies are needed to characterize this relationship.
MATERIALS AND METHODS: In this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed.
RESULTS: The mean level of homocysteine was 16.25 ± 11.94 μmol/L in patients with PCOS and 11.58 ± 3.82 μmol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for hyperhomocysteinemia compared with BMI-matched control women.
CONCLUSION: These data suggest that homocysteine levels are elevated in the PCOS population. Further studies are needed to characterize this relationship.