Tamoxifen retinopathy. A case report.

Tamoxifen is one of the most effective anti-estrogens for breast carcinoma therapy and has been used since 1971. Side effects are not frequent, but some ophthalmologic complications have already been described such as retinopathy, keratopathy and optic neuritis. The authors report a case of retinopathy occurring after a period of 7 years (205 g total doses). They give a review of the literature, with the ophthalmological and functional aspects of the retinopathy.