Медицинская библиотека · Revista da Sociedade Brasileira de Medicina Tropical · 2015

Detection of Leishmania (Viannia) DNA in leucocytes from the blood of patients with cutaneous leishmaniasis.

Conter Carolina Cella, Neitzke-Abreu Herintha Coeto, Pedroso Raissa Bocchi, Lonardoni Maria Valdrinez Campana, Silveira Thaís Gomes Verzignassi, Aristides Sandra Mara Alessi

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Аннотация

INTRODUCTION

Cutaneous leishmaniasis (CL) is a serious and global public health issue, with the potential of developing a mucosal form, occurring as subclinical cases, and showing recurrence despite previous treatment.

METHODS

Polymorphonuclear and mononuclear DNA obtained from 49 patients was subjected to polymerase chain reaction for detection of Leishmania (Viannia).

RESULTS

DNA was detected in mononuclear cells from two patients with active primary lesions positive for CL, with infection periods of 3 and 6 months, respectively.

CONCLUSIONS

The DNA of Leishmania (Viannia) indicates probable parasite dissemination possibly explaining subclinical case emergence, lesion recurrence, and mucosal lesion appearance.

Для цитирования: Conter Carolina Cella, Neitzke-Abreu Herintha Coeto, Pedroso Raissa Bocchi, Lonardoni Maria Valdrinez Campana, Silveira Thaís Gomes Verzignassi, Aristides Sandra Mara Alessi. Detection of Leishmania (Viannia) DNA in leucocytes from the blood of patients with cutaneous leishmaniasis.. Revista da Sociedade Brasileira de Medicina Tropical. 2015. DOI: 10.1590/0037-8682-0052-2015.

Предметные рубрики MeSH

DNA, Protozoan Female Humans Leishmania Leishmaniasis, Cutaneous Leukocytes, Mononuclear Male Polymerase Chain Reaction

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