Cornea · 2008
Manual trephination of mushroom keratoplasty in advanced keratoconus.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Saelens Isabelle E Y, Bartels Marjolijn C, Van Rij Gabriel
Аннотация
PURPOSE: To evaluate the technique of mushroom keratoplasty for patients with advanced keratoconus, with respect to postoperative astigmatism, visual improvement and stability, and endothelial cell count.
METHODS: Sixteen eyes of 15 patients with advanced keratoconus received a mushroom keratoplasty at the Erasmus Medical Centre at Rotterdam between April 2003 and May 2006. The donor cornea had a larger anterior stromal lamella (9.0 mm) and a smaller posterior part (7.0 mm). Visual acuity and keratometry were measured at 6, 12, 24, and 36 months. Specular microscopy was performed annually.
RESULTS: Best-corrected visual acuity improved significantly (P = 0.003) from 0.25 +/- 0.20 preoperatively to 0.62 +/- 0.22 at 6 months postoperatively. Visual acuity remained stable with a best-corrected visual acuity of 0.70 +/- 0.22 from 1 year onward. At all follow-up periods, mean postoperative astigmatism remained <3.5 D. Mean postoperative astigmatism at 1, 2, and 3 years measured 2.67 +/- 1.95 (n = 15), 2.54 +/- 1.86 (n = 6), and 3.30 +/- 2.12 D (n = 5). The average endothelial cell count at 1 and 2 years was 1755 +/- 678 (n = 12) and 1573 +/- 546 cells/mm2 (n = 5), respectively. At the end of follow-up, all transplants remained functional and clear.
CONCLUSIONS: The mushroom-shaped graft can combine the benefits of a good visual acuity, a low astigmatism, and rapid postoperative healing. The short-term results of our limited series of patients are encouraging. Further research is necessary to draw stronger conclusions regarding the long-term effects.
METHODS: Sixteen eyes of 15 patients with advanced keratoconus received a mushroom keratoplasty at the Erasmus Medical Centre at Rotterdam between April 2003 and May 2006. The donor cornea had a larger anterior stromal lamella (9.0 mm) and a smaller posterior part (7.0 mm). Visual acuity and keratometry were measured at 6, 12, 24, and 36 months. Specular microscopy was performed annually.
RESULTS: Best-corrected visual acuity improved significantly (P = 0.003) from 0.25 +/- 0.20 preoperatively to 0.62 +/- 0.22 at 6 months postoperatively. Visual acuity remained stable with a best-corrected visual acuity of 0.70 +/- 0.22 from 1 year onward. At all follow-up periods, mean postoperative astigmatism remained <3.5 D. Mean postoperative astigmatism at 1, 2, and 3 years measured 2.67 +/- 1.95 (n = 15), 2.54 +/- 1.86 (n = 6), and 3.30 +/- 2.12 D (n = 5). The average endothelial cell count at 1 and 2 years was 1755 +/- 678 (n = 12) and 1573 +/- 546 cells/mm2 (n = 5), respectively. At the end of follow-up, all transplants remained functional and clear.
CONCLUSIONS: The mushroom-shaped graft can combine the benefits of a good visual acuity, a low astigmatism, and rapid postoperative healing. The short-term results of our limited series of patients are encouraging. Further research is necessary to draw stronger conclusions regarding the long-term effects.