Spinal cord · 2025
Spinal cord injury research and national institutes of health funding: a call to action.
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Silvestre Jason, Martin John C, Roth Warren, Ferdon Robert J, Reitman Charles A, Lawrence James P, Fehlings Michael G, Ravinsky Robert A
Аннотация
STUDY DESIGN: Cross-sectional study.
OBJECTIVES: The magnitude and nature of National Institutes of Health (NIH) funding for spinal cord injury (SCI) research is poorly characterized. This study elucidates the portfolio of NIH grants awarded for SCI research.
SETTING: N/A METHODS: Data on NIH grants awarded for SCI research were extracted from the NIH RePORTER database (2013-2023). NIH funding was analyzed for twenty-five clinical areas and compound annual growth rates (CAGRs) were calculated over the study period.
RESULTS: From 2013-2023, the NIH extramural research budget increased from $28.3 to $45.0 billion (CAGR 4.7%). A total of $986 million was awarded for SCI research, which increased from $93.6 to $97.7 million over the study period (CAGR 0.4%). Among the twenty-five clinical areas, dementia ($21.8 billion, CAGR 18.7%) and diabetes ($20.6 billion, CAGR 21.5%) had the most NIH funding. For SCI research, most NIH funding was awarded by the National Institute of Neurological Disorders and Stroke (67%) via the R01 (57%) grant mechanism. The clinical areas receiving the most NIH funding for SCI research were disease mechanisms (47%), prosthetics (22%), biologic therapies (18%), and pharmacologic therapies (6%). Several principal investigator characteristics were associated with higher NIH funding totals for SCI research including male (P < 0.001), full professor (P < 0.001), and MD, PhD degree (P = 0.044).
CONCLUSIONS: Growth in the annual NIH budget for SCI research has not kept pace with growth in the overall NIH extramural research budget. Future strategies are needed to support PIs in obtaining NIH grant funding for SCI research.
OBJECTIVES: The magnitude and nature of National Institutes of Health (NIH) funding for spinal cord injury (SCI) research is poorly characterized. This study elucidates the portfolio of NIH grants awarded for SCI research.
SETTING: N/A METHODS: Data on NIH grants awarded for SCI research were extracted from the NIH RePORTER database (2013-2023). NIH funding was analyzed for twenty-five clinical areas and compound annual growth rates (CAGRs) were calculated over the study period.
RESULTS: From 2013-2023, the NIH extramural research budget increased from $28.3 to $45.0 billion (CAGR 4.7%). A total of $986 million was awarded for SCI research, which increased from $93.6 to $97.7 million over the study period (CAGR 0.4%). Among the twenty-five clinical areas, dementia ($21.8 billion, CAGR 18.7%) and diabetes ($20.6 billion, CAGR 21.5%) had the most NIH funding. For SCI research, most NIH funding was awarded by the National Institute of Neurological Disorders and Stroke (67%) via the R01 (57%) grant mechanism. The clinical areas receiving the most NIH funding for SCI research were disease mechanisms (47%), prosthetics (22%), biologic therapies (18%), and pharmacologic therapies (6%). Several principal investigator characteristics were associated with higher NIH funding totals for SCI research including male (P < 0.001), full professor (P < 0.001), and MD, PhD degree (P = 0.044).
CONCLUSIONS: Growth in the annual NIH budget for SCI research has not kept pace with growth in the overall NIH extramural research budget. Future strategies are needed to support PIs in obtaining NIH grant funding for SCI research.