The Canadian veterinary journal = La revue veterinaire canadienne · 2023
Canine hypoadrenocorticism: Insights into the Addisonian crisis.
СтатьяНазвание и аннотация: Перевод в очереди
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Chalifoux Nolan V, Burgess Hilary J, Feng Cindy X, Kong Lyndsay R, Snead Elisabeth C R
Аннотация
OBJECTIVE: Primary objectives of this study were to determine presenting complaints, physical examination, clinicopathologic findings, and hospitalization time of dogs with spontaneous hypoadrenocorticism presenting with critical disease; and to compare those end points to dogs with a more stable presentation. Secondary objectives were to evaluate the shock index and to identify precipitating stressors.
ANIMALS: Eighty-four dogs at the Western College of Veterinary Medicine between 1998 and 2018 were included.
PROCEDURE: Data were retrieved from the medical records.
RESULTS: Collapse and depression were more common among critically ill dogs. Hyperlactatemia was rare despite a diagnosis of hypovolemic shock, and a shock index was ineffective in this patient subset. Isosthenuria, total hypocalcemia, and more severe acidosis were more common (P < 0.05) in critical dogs. Owner separation was the most common precipitating stressor.
CONCLUSION AND CLINICAL RELEVANCE: We concluded that the critical Addisonian dog has unique characteristics that may aid in early disease identification.
ANIMALS: Eighty-four dogs at the Western College of Veterinary Medicine between 1998 and 2018 were included.
PROCEDURE: Data were retrieved from the medical records.
RESULTS: Collapse and depression were more common among critically ill dogs. Hyperlactatemia was rare despite a diagnosis of hypovolemic shock, and a shock index was ineffective in this patient subset. Isosthenuria, total hypocalcemia, and more severe acidosis were more common (P < 0.05) in critical dogs. Owner separation was the most common precipitating stressor.
CONCLUSION AND CLINICAL RELEVANCE: We concluded that the critical Addisonian dog has unique characteristics that may aid in early disease identification.