First episode mania following cessation of varenicline (Champix).

OBJECTIVES

To describe a case of first episode mania and in which varenicline (Champix) or its withdrawal appears to have been the precipitating factor.

METHODS

The clinical presentation and progress are detailed and the relevant literature in relation to varenicline is provided.

RESULTS

The case report adds to the literature indicating that varenicline may induce a range of mood states, albeit with reported incidents of mania being rare.

CONCLUSIONS

In reviewing causes of mood states, including mania, seeking information on any exposure to varenicline would appear to be relevant.