Gan to kagaku ryoho. Cancer & chemotherapy · 2017
[A Case of a Two-Stage Hepatectomy for Irresectable Colorectal Cancer Liver Metastases].
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Yukawa Yoshiro, Murata Kohei, Kagawa Yoshinori, Sakamoto Takuya, Inatome Junichi, Naito Atsushi, Murakami Kohei, Katsura Yoshiteru, Ohmura Yoshiaki, Takeno Atsushi, Egawa Chiyomi, Nakatsuka Shinichi, Kato Takeshi, Tamura Shigeyuki, Takeda Yutaka
Аннотация
A 60-year-oldman was diagnosedwith ascending colon cancer with multiple bilobar metastases. He then received7 courses of tegafur-gimeracil-oteracil andoxaliplatin (SOX)plus panitumumab as downstaging chemotherapy. This treatment significantly reducedthe size of the metastatic tumor, andwe subsequently triedto perform a curative resection. A twostage hepatectomy was plannedto avoidthe risk of hepatic failure from small future liver remnant. First, the anterior segmentectomy andthe left portal vein ligation were performed. Then, a curative resection consisting of a left lobectomy andextend - edright hemicolectomy were performed2 0 days after the first surgery. No recurrence was observed1 5 months after the operation. Two-stage hepatectomy as well as a combination of induction chemotherapy and portal vein ligation may have contributedto the improvedprognosis of the initially unresectable multiple bilobar liver metastases.