Recent trends and perspectives on malaria relapse: A mini review.

Worldwide elimination of malaria remains a challenge yet to be accomplished, and the domain of malaria relapse remains equally obtuse. Yet, sophisticated cell culture and screening techniques and animal models are being constructed and molecular regulations are discovered in this intriguing discipline. An elaborate understanding of these schemes is mandatory to conceive effective therapeutic strategies. Hence, this review details the landmark paradigms, technical advances and novel clinical interventions pertaining to malaria relapse. Keywords such as 'Malaria', 'Vivax Relapse' and 'Hypnozoites' were selected from PubMed database and data were duly extracted to be synthesized. In addition, special attention was given to the molecular nature and activation of hypnozoites and sexual cycles of parasites in the context of malaria relapse biology.