Dermatology (Basel, Switzerland) · 2014
Self-reported skin morbidities and health-related quality of life: a population-based nested case-control study.
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Vinding G R, Knudsen K M, Ellervik C, Olesen A B, Jemec G B E
Аннотация
BACKGROUND: Impaired dermatological health-related quality of life (HRQoL) has been observed in hospital-based studies, but little is known on a population-based level.
OBJECTIVE: To investigate self-reported dermatological HRQoL in the general population.
METHODS: Hidradenitis suppurativa, psoriasis, pimples, hand rash or atopic eczema were identified using questionnaires in a 15,177 person population sample. A nested case-control study of 180 cases and 259 controls was made using the Dermatology Life Quality Index (DLQI), Skindex-29 and EQ-5D.
RESULTS: Cases had higher scores in DLQI and Skindex-29 and a lower score in EQ-5D, suggesting lower HRQoL. Adjusting for age and sex, the differences in Skindex-29 and DLQI were significant (p < 0.001).
CONCLUSIONS: Persons with self-reported skin morbidity had lower HRQoL than the general population. The impairment is not as significant as in studies of hospital-based cases, but considering the high prevalence of skin diseases it may still represent a significant burden of disease on society in aggregate.
OBJECTIVE: To investigate self-reported dermatological HRQoL in the general population.
METHODS: Hidradenitis suppurativa, psoriasis, pimples, hand rash or atopic eczema were identified using questionnaires in a 15,177 person population sample. A nested case-control study of 180 cases and 259 controls was made using the Dermatology Life Quality Index (DLQI), Skindex-29 and EQ-5D.
RESULTS: Cases had higher scores in DLQI and Skindex-29 and a lower score in EQ-5D, suggesting lower HRQoL. Adjusting for age and sex, the differences in Skindex-29 and DLQI were significant (p < 0.001).
CONCLUSIONS: Persons with self-reported skin morbidity had lower HRQoL than the general population. The impairment is not as significant as in studies of hospital-based cases, but considering the high prevalence of skin diseases it may still represent a significant burden of disease on society in aggregate.
Предметные рубрики MeSH
Acne VulgarisAdaptation, PsychologicalAdultAge FactorsAnalysis of VarianceCase-Control StudiesChronic DiseaseConfidence IntervalsCross-Sectional StudiesDenmarkEczemaFemaleHand DermatosesHumansMaleMiddle AgedPsoriasisQuality of LifeRisk AssessmentSelf ReportSex FactorsSickness Impact ProfileSkin DiseasesSurveys and QuestionnairesYoung Adult