Retinal vasculopathy associated with mixed connective tissue disease.

PURPOSE: To report an intractable case of retinal vasculopathy associated with mixed connective tissue disease (MCTD).

DESIGN

Case report.

METHODS

Interventional case report.

RESULTS

A 35-year-old woman presented with decreased visual acuity and multiple retinal hemorrhages and macular edema in her right eye. She had a history of central retinal vein occlusion in the opposite eye and MCTD. Her clinical course deteriorated despite subsequent systemic and intravitreal steroid and immunosuppressant treatments. The retinal vasculopathy involved both artery and vein, causing wide retinal areas of nonperfusion. Her final visual acuity was hand motion.

CONCLUSIONS

MCTD may be associated with bilateral vasculopathy that is refractory to systemic steroid, intravitreal steroid, and immunosuppressant treatment.