[Clinical and pathogenetic rationale of the gallstone disease combines with duodenal ulcer].

In this article you will find the clinical features of the course of gallstone disease (GSD) and duodenal ulcer (DU) when they are combined and given to their pathogenetic substantiation. There were shown data analysis of the frequency combinations of GSD and DU, depending on age and sex. It was found that at GSD was observed decrease in the frequency of exacerbations of DU until the development of stable remission. The presence of DU, in turn, reduces the frequency of exacerbations of GSD (biliary colic), the severity of its clinical manifestations, which leads to an increase in patients with asymptomatic "stone living". These clinical features are associated with reduced secretion of gastrointestinal hormones (gastrin, cholecystokinin).