European journal of obstetrics, gynecology, and reproductive biology · 2025
Pregnancy and delivery in a woman with spinal muscular atrophy type III.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Shi Yunfang, Zhao Linwei, Meng Fanrong, Ju Duan, Wang Xiuyan, Zhou Xinghong, Li Xiaozhou
Аннотация
OBJECTIVES: To investigate the perinatal management of a spinal muscular atrophy (SMA) patient during pregnancy.
METHODS: A pregnant woman with SMA type III was admitted to Tianjin Medical University General Hospital for prenatal diagnosis and perinatal care.
RESULTS: The pregnant woman was diagnosed with SMA type III based on clinical observations and genetic tests. The results of amniocentesis indicated that the fetus was a carrier of SMA. An elective cesarean section was arranged at 35+3 weeks. Throughout the follow-up period, the patient's SMA symptoms essentially reverted to their pregestational level without any significant exacerbation.
CONCLUSIONS: Genetically confirmed SMA patients in China remain scarce, and those with SMA who are capable of conceiving are even rarer. It is recommended that Patients with SMA undergo prenatal diagnosis and receive pregnancy check-ups and deliveries at a tertiary care hospital with an interdisciplinary medical team.
METHODS: A pregnant woman with SMA type III was admitted to Tianjin Medical University General Hospital for prenatal diagnosis and perinatal care.
RESULTS: The pregnant woman was diagnosed with SMA type III based on clinical observations and genetic tests. The results of amniocentesis indicated that the fetus was a carrier of SMA. An elective cesarean section was arranged at 35+3 weeks. Throughout the follow-up period, the patient's SMA symptoms essentially reverted to their pregestational level without any significant exacerbation.
CONCLUSIONS: Genetically confirmed SMA patients in China remain scarce, and those with SMA who are capable of conceiving are even rarer. It is recommended that Patients with SMA undergo prenatal diagnosis and receive pregnancy check-ups and deliveries at a tertiary care hospital with an interdisciplinary medical team.