Neuroleptic-induced Tardive Tourette treated with clonazepam: a case report and literature review.

Tardive Tourette syndrome has been reported as a rare complication of neuroleptic treatment. This report describes the first case of neuroleptic-induced tardive Tourette syndrome in the Latin Americas and supports the successful treatment of this disorder with clonazepam. The syndrome developed in a female schizophrenic patient who discontinued medication after 8 years of continuous neuroleptic therapy. Symptoms were unresponsive to increased doses of typical antipsychotics and treatment with an atypical antipsychotic. Significant, sustained improvement occurred with clonazepam. In this report all cases of adult-onset tardive Tourette are reviewed.