Archives of pathology & laboratory medicine · 2025
Diagnostic Pearls and Pitfalls in the Evaluation of Small Biopsies From the Bile Duct and Ampulla.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Krasinskas Alyssa M
Аннотация
CONTEXT.—: Histopathologic evaluation of bile duct and ampullary biopsies can be challenging. Biopsies from these sites are often tiny, scant, and/or fragmented. When assessing these biopsies, there is significant overlap between reactive atypia and malignancy, in situ precursor lesions can be misinterpreted as malignancy, and nonprimary tumors can mimic primary disease.
OBJECTIVE.—: To provide diagnostic pearls and pitfalls in the evaluation of small biopsies from the biliary tract.
DATA SOURCES.—: Literature review of published studies and the author's own observations.
CONCLUSIONS.—: Because the procedures for obtaining specimens from the bile duct and ampulla are invasive, pathologists need to try to make definitive diagnoses. Diagnostic clues/pearls, ancillary studies, and recognition of various pitfalls can assist in providing accurate and confident diagnoses.
OBJECTIVE.—: To provide diagnostic pearls and pitfalls in the evaluation of small biopsies from the biliary tract.
DATA SOURCES.—: Literature review of published studies and the author's own observations.
CONCLUSIONS.—: Because the procedures for obtaining specimens from the bile duct and ampulla are invasive, pathologists need to try to make definitive diagnoses. Diagnostic clues/pearls, ancillary studies, and recognition of various pitfalls can assist in providing accurate and confident diagnoses.