Transactions of the Royal Society of Tropical Medicine and Hygiene · 1985
Detection of antibodies in strongyloidiasis by enzyme-linked immunosorbent assay (ELISA).
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Sato Y, Takara M, Otsuru M
Аннотация
Detection of IgG antibodies to Strongyloides stercoralis in sera of 29 patients with strongyloidiasis was attempted by the enzyme-linked immunosorbent assay (ELISA) using an extract of filariform larvae of S. stercoralis. The antibodies were found with a high degree of sensitivity in almost all patients. The ELISA values, however, did not correlate with the intensity of the infection or with differences in clinical and laboratory parameters. When the ELISA values of persons with Strongyloides were compared with those showing no S. stercoralis by faecal examinations, a significant difference was obtained between these two groups. The cross reactions with other helminth infections were significantly weaker than the reaction with Strongyloides infection. It was concluded that the antibodies are strongly elicited in human strongyloidiasis and that the assay provides a sensitive and specific method for diagnosis of strongyloidiasis.