Gan to kagaku ryoho. Cancer & chemotherapy · 2020
[Esophagogastric Junctional Adenocarcinoma Responding Completely to Chemotherapy in an Elderly Patient with Long-Term Survival and No Recurrences-A Case Report].
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kuwabara Hiroshi, Katayanagi So, Koganezawa Itsuki, Yokozuka Kei, Tabuchi Satoru, Kawachi Shigeyuki
Аннотация
An 85-year-old man was diagnosed with esophagogastric junctional adenocarcinoma, E=G, Type 2, por, 6 cm in size, cT4aN1M0, cStage ⅢA. He had a history of atherosclerosis obliterans and thoracoabdominal aortic aneurysm. Considering the comorbidities and life expectancy, we decided to perform chemotherapy without tumor resection. Although the renal function was poor, we chose SP therapy(S-1 80mg/kg/day for 14 days, followed by 7-day rest, CDDP 30mg/kg/day on day 1)because the current status of the patient was satisfactory. The primary tumor remarkably shrank after 2 courses of SP therapy and completely disappeared after 5 courses of SP therapy. There were no adverse events during the entire course of treatment. We detected clinical CR and provided the S-1 monotherapy for another 2 years. The patient has survived with no recurrences for 7 years since the initial chemotherapy. Although intensive chemotherapy regimens are avoided in elderly patients, the patient, in this case, showed a favorable prognosis from powerful chemotherapy.