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Gan to kagaku ryoho. Cancer & chemotherapy · 2020

[Esophagogastric Junctional Adenocarcinoma Responding Completely to Chemotherapy in an Elderly Patient with Long-Term Survival and No Recurrences-A Case Report].

Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Kuwabara Hiroshi, Katayanagi So, Koganezawa Itsuki, Yokozuka Kei, Tabuchi Satoru, Kawachi Shigeyuki

Аннотация

An 85-year-old man was diagnosed with esophagogastric junctional adenocarcinoma, E=G, Type 2, por, 6 cm in size, cT4aN1M0, cStage ⅢA. He had a history of atherosclerosis obliterans and thoracoabdominal aortic aneurysm. Considering the comorbidities and life expectancy, we decided to perform chemotherapy without tumor resection. Although the renal function was poor, we chose SP therapy(S-1 80mg/kg/day for 14 days, followed by 7-day rest, CDDP 30mg/kg/day on day 1)because the current status of the patient was satisfactory. The primary tumor remarkably shrank after 2 courses of SP therapy and completely disappeared after 5 courses of SP therapy. There were no adverse events during the entire course of treatment. We detected clinical CR and provided the S-1 monotherapy for another 2 years. The patient has survived with no recurrences for 7 years since the initial chemotherapy. Although intensive chemotherapy regimens are avoided in elderly patients, the patient, in this case, showed a favorable prognosis from powerful chemotherapy.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты