Cirugia y cirujanos · 2020
Outcome of multidisciplinary treatment in laryngeal cancer. Retrospective study with 10-years follow-up.
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Gurrola-Machuca Héctor, Miranda-Aguirre Arturo P, Villavicencio-Quejeiro Michelle, Nuñez-Guardado Gabriela, Juárez-Ramiro Alejandro
Аннотация
BACKGROUND: In laryngeal cancer, multidisciplinary treatment improves the patient's quality of life and the possibility of preserving the larynx. Most cases occur in a locally advanced stage. The aim is to present the results according to the stage.
METHOD: A retrospective study which analyzed the clinical stage, type of primary treatment, outcomes, and survival were analyzed.
RESULTS: 451 patients were included. The median age was 66 years. The majority of the tumors presented in advanced stage (72%) and the most affected subsite was the glottis (84.5%). In the early stage the most frequent treatment was radiotherapy as the only treatment modality. In stages III and IVA, 65% were resectable. In stage IVB the management was non-surgical, with control in 26% of the cases. Survival at 10 years was related to the clinical stage: 81.7% for stage I and 0% for stages IVB and IVC.
CONCLUSIONS: Patients with laryngeal cancer should be treated according to the clinical stage, through a multidisciplinary approach. Long-term follow-up showed a worse prognosis for advanced clinical stages.
METHOD: A retrospective study which analyzed the clinical stage, type of primary treatment, outcomes, and survival were analyzed.
RESULTS: 451 patients were included. The median age was 66 years. The majority of the tumors presented in advanced stage (72%) and the most affected subsite was the glottis (84.5%). In the early stage the most frequent treatment was radiotherapy as the only treatment modality. In stages III and IVA, 65% were resectable. In stage IVB the management was non-surgical, with control in 26% of the cases. Survival at 10 years was related to the clinical stage: 81.7% for stage I and 0% for stages IVB and IVC.
CONCLUSIONS: Patients with laryngeal cancer should be treated according to the clinical stage, through a multidisciplinary approach. Long-term follow-up showed a worse prognosis for advanced clinical stages.
Предметные рубрики MeSH
AdultAgedAged, 80 and overAntineoplastic Agents, ImmunologicalCarcinoma, Squamous CellCetuximabCombined Modality TherapyFemaleFollow-Up StudiesGlottisHumansInduction ChemotherapyLaryngeal NeoplasmsLaryngectomyMaleMiddle AgedNeoplasm Recurrence, LocalPrognosisRadiotherapyRetrospective StudiesTime Factors