Advances in inherited disorders of hypopigmentation: comparisons of mice and men.

This review highlights recent advances in the localization of genes responsible for selected inherited disorders of hypopigmentation including Piebaldism, Waardenburg's syndrome, Menkes' disease, as well as oculocutaneous and ocular albinism. Human and mouse homologous sequences, linkage analysis, and cytogenetic studies of affected individuals are powerful tools to identify these loci.