bioRxiv : the preprint server for biology · 2026

Dispersal, adaptation and persistence of H5N1 in the sub-Antarctic and Antarctica.

СтатьяПрепринтНазвание и аннотация: Перевод пока не подготовлен

Обработка статьи · этапы, ошибки и управление

Загрузка состояния…

История · было → стало

Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.

Clessin Augustin, Brusselmans Marius, Hong Samuel L, Tornos Jérémy, Lejeune Mathilde, Shao Yucai, Briand François-Xavier, Abolnik Celia, Kaza Benjamin, Suchard Marc A, Aguado Begoña, Alcamí Antonio, Barbraud Christophe, Beer Martin, Bennison Ashley, Bonadonna Francesco, Bonnet Timothée, Bost Charles-André, Boucheron Sara, Bralet Tristan, Catry Paulo, Cleeland Jaimie, Connan Maelle, Coombes Holly A, Delord Karine, de Pasquale Camille, Dewar Meagan L, Dong Xiaomin, Emerit Julia, Fischer Romain, Fountain-Jones Nicholas, Galimberti Filippo, González-Solís Jacob, Guinet Christophe, Gunn Carrie, Günther Anne, Iervolino Matteo, James Joe, Ji Xiang, Jonsen Ian, Jones Christopher W, Kuepfer Amanda, Kuiken Thijs, Lebohec Céline, Lisovski Simeon, Llorente Zubiri Lucia, Lynton-Jenkins Joshua G, Martinez-García Paula, McCulley Michelle, McMahon Clive R, Mollett Benjamin C, Moraga-Quintanilla Ana I, Nichol Rhiannon, Noiret Aude, Ogrzewalska Maria, Owen Kate, Pardo-Roa Catalina, Peroteau Samuel, Phillips Richard A, Poulin Elie, Rambaut Andrew, Reid Scott M, Riehle Eva, Risi Michelle, Rumianowski Odin, Ryan Peter G, Sanvito Simona, Stanworth Andrew, Steinfurth Antje, Stevenson Jonathon, Stier Antoine, Uhart Marcela M, Vanstreels Ralph E T, Vázquez-Calvo Angela, Vianna Juliana A, Wells Katie, White Jeff, Whitelaw Paul, Wille Michelle, Younger Jane, Roberts Laura C, Grasland Béatrice, Banyard Ashley C, Nelson Martha I, Gamble Amandine, Boulinier Thierry, Baele Guy

Аннотация

High pathogenicity avian influenza virus (HPAIV) H5N1 reached the sub-Antarctic and Antarctica in 2023, subsequently spreading to remote locations within this region where it had devastating impacts on seal, penguin and albatross populations. The threat to marine wildlife over this broad area exemplifies the need to understand H5N1 long-distance dispersal and evolution. We obtained 104 novel viral genomic sequences from samples that we collected at South Georgia, Kerguelen, Crozet, Prince Edward, Falklands/Malvinas Islands and the Antarctic Peninsula in a region spanning 8,000 kilometers. Using recent phylogeographic modeling advances we show that H5N1 spread encompassed numerous transmission events between distant locations, accumulating mammalian-adaptive mutations in the process. Seals are the most affected species, but we reveal that the long-distance eastward virus dispersal better aligns with the long-distance movements of large petrels and albatrosses. The risk of H5N1 endemisation, dispersal to other locations and ongoing evolution are highly concerning.

Dispersal, adaptation and persistence of H5N1 in the sub-Antarctic and Antarctica.

Ошибки и ограничения

Аннотация