Медицинская библиотека · Current neurology and neuroscience reports · 2024

CGRP Modulating Therapies: An Update.

Bedrin Kate, Shah Tulsi, Vaidya Shivani, Ailani Jessica

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Аннотация

INTRODUCTION

Calcitonin-gene related peptide (CGRP) is a vasoactive neuropeptide involved in the pathophysiology ofmigraine. CGRP has been targeted for both preventive and acute treatment of migraine.

OBJECTIVE

Provide a summary of the most clinically relevant literature surrounding CGRP modulating therapies.

METHODS

This update on CGRP modulating therapies includes articles selected as most clinically relevant by theauthors.

CONCLUSION

CGRP modulating therapies are an exciting new addition to migraine treatment given their safety andtolerability. Additionally, compared to traditional migraine preventive medication these treatments are migrainespecific.Further real-world and clinical data is ongoing to better understand these treatments that continue to gainfavor in the management of migraine.

Для цитирования: Bedrin Kate, Shah Tulsi, Vaidya Shivani, Ailani Jessica. CGRP Modulating Therapies: An Update.. Current neurology and neuroscience reports. 2024. DOI: 10.1007/s11910-024-01363-w.

Предметные рубрики MeSH

Humans Migraine Disorders Calcitonin Gene-Related Peptide Calcitonin Gene-Related Peptide Receptor Antagonists

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