European journal of clinical nutrition · 1995
Application of the modified relative dose response test to pregnant Indonesian women for assessing vitamin A status.
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Tanumihardjo S A, Suharno D, Permaesih D, Muherdiyantiningsih, Dahro A M, Muhilal, Karyadi D, Olson J A
Аннотация
OBJECTIVE: To determine the prevalence of subclinical vitamin A deficiency (vitamin A inadequacy) in Indonesian pregnant women as assessed by the modified relative dose response test.
DESIGN: Cross-sectional study of the vitamin A statuses of pregnant (second trimester) women randomly selected from ten different villages.
SETTING: West Java, Indonesia.
SUBJECTS: A group of 144 pregnant women recruited from the local health posts.
INTERVENTIONS: Modified relative dose response (MRDR) test, serum retinol determination and gynecological examinations.
RESULTS: The mean (s.d.) MRDR ratio was 0.039 +/- 0.031. Of the women tested, the vitamin A status of 17% was provisionally classified as being marginal (subclinically deficient) (MRDR ratio > or = 0.060), of 35% as being uncertain (MRDR ratio between 0.030 and 0.060) and of 48% as being satisfactory (MRDR ratio < or = 0.030).
CONCLUSION: If the vitamin A statuses of the 'uncertain' group are also deemed to be unsatisfactory, approximately half of the pregnant Indonesian women tested could benefit from an increased intake of vitamin A.
DESIGN: Cross-sectional study of the vitamin A statuses of pregnant (second trimester) women randomly selected from ten different villages.
SETTING: West Java, Indonesia.
SUBJECTS: A group of 144 pregnant women recruited from the local health posts.
INTERVENTIONS: Modified relative dose response (MRDR) test, serum retinol determination and gynecological examinations.
RESULTS: The mean (s.d.) MRDR ratio was 0.039 +/- 0.031. Of the women tested, the vitamin A status of 17% was provisionally classified as being marginal (subclinically deficient) (MRDR ratio > or = 0.060), of 35% as being uncertain (MRDR ratio between 0.030 and 0.060) and of 48% as being satisfactory (MRDR ratio < or = 0.030).
CONCLUSION: If the vitamin A statuses of the 'uncertain' group are also deemed to be unsatisfactory, approximately half of the pregnant Indonesian women tested could benefit from an increased intake of vitamin A.