Primary Hyper-aldosteronism in pregnancy: a case report with review of the literature.

OBJECTIVES

Primary hyperaldosteronism can present during pregnancy. Due to its rarity and to the physiological changes occurring during pregnancy, diagnosis might be delayed with potential complications imposed on the mother and newborn.

CASE PRESENTATION: We report a 46-years-old middle eastern patient with chronic hypertension, who conceived with assisted reproductive technologies and was diagnosed with PA. She was referred back to cardiology for re-evaluation of her resistant hypertension. Serum electrolytes showed low potassium, high aldosterone, and high renin to aldosterone ratio. Magnetic resonance imaging of the adrenal glands revealed a unilateral nodule in the left adrenal gland. The patient was maintained on three antihypertensives; unfortunately, her pregnancy was complicated by intrauterine growth restriction and preterm delivery for preeclampsia with severe features.

CONCLUSIONS

Primary hyperaldosteronism is a rare complication of pregnancy that is challenging to diagnose. However, timely and accurate diagnosis are essential to initiate appropriate treatment to ensure optimal fetal and maternal outcomes.