Gastroenterologia y hepatologia · 2026
Mental Health and quality of Life in Inflammatory Bowel disease: Cross-sectional Study on its Impact.
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Gallardo Arriero Vanesa, Calvo Moya Marta, de Lucas Téllez de Meneses Rocío, González Partida Irene, Botella Mateu Belén, Matallana Royo Virginia, Bella Castillo Pablo, González Rodríguez Macarena, Vera Mendoza Maribel
Аннотация
OBJECTIVE: Inflammatory Bowel Disease (IBD) negatively impacts patients' quality of life. This study aims to evaluate the psychological impact and quality of life in patients with IBD.
PATIENTS AND METHODS: A cross-sectional study was conducted involving IBD patients treated at HUPHM. Validated questionnaires were used to assess patients' mental health. Clinical activity was evaluated using the Harvey-Bradshaw Index and the Partial Mayo Score. Clinical data were also collected.
RESULTS: A total of 272 patients were included. Seventy-eight percent experienced some degree of psychological impairment, and 68% reported a negative impact on their quality of life. Anxiety showed a median score of 11 (IQR: 10-13) and stress a median of 24 (IQR: 16-31), representing the most frequent psychological disturbances. Quality of life and fatigue results reflected significant impairment, with fatigue being more prevalent in women (52%, p=0.027) and associated with higher stress levels (p=0.0013) and poorer quality of life (p=0.014). Patients with Crohn's disease exhibited worse quality of life compared to those with ulcerative colitis (median score: 46 [IQR: 34-55] vs. 49 [IQR: 41-55], p=0.04). In the occupational domain, patients with work disability showed greater psychological impairment and poorer quality of life (p=0.001). Finally, patients without prior surgery demonstrated better quality of life (p=0.032).
CONCLUSIONS: The high prevalence of psychological comorbidities in IBD highlights the need for approaches that incorporate psychological assessment and intervention.
PATIENTS AND METHODS: A cross-sectional study was conducted involving IBD patients treated at HUPHM. Validated questionnaires were used to assess patients' mental health. Clinical activity was evaluated using the Harvey-Bradshaw Index and the Partial Mayo Score. Clinical data were also collected.
RESULTS: A total of 272 patients were included. Seventy-eight percent experienced some degree of psychological impairment, and 68% reported a negative impact on their quality of life. Anxiety showed a median score of 11 (IQR: 10-13) and stress a median of 24 (IQR: 16-31), representing the most frequent psychological disturbances. Quality of life and fatigue results reflected significant impairment, with fatigue being more prevalent in women (52%, p=0.027) and associated with higher stress levels (p=0.0013) and poorer quality of life (p=0.014). Patients with Crohn's disease exhibited worse quality of life compared to those with ulcerative colitis (median score: 46 [IQR: 34-55] vs. 49 [IQR: 41-55], p=0.04). In the occupational domain, patients with work disability showed greater psychological impairment and poorer quality of life (p=0.001). Finally, patients without prior surgery demonstrated better quality of life (p=0.032).
CONCLUSIONS: The high prevalence of psychological comorbidities in IBD highlights the need for approaches that incorporate psychological assessment and intervention.