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DOI 10.18632/oncotarget.8037

Медицинская библиотека · Neurologia i neurochirurgia polska · 2007

[Deep brain stimulation of the ventral intermediate thalamic nucleus in the treatment of essential tremor].

Li Zai-Shang, Chen Peng, Yao Kai, Wang Bin, Li Jing, Mi Qi-Wu, Chen Xiao-Feng, Zhao Qi, Li Yong-Hong, Chen Jie-Ping, Deng Chuang-Zhong, Ye Yun-Lin, Zhong Ming-Zhu, Liu Zhuo-Wei, Qin Zi-Ke, Lin Xiang-Tian, Liang Wei-Cong, Han Hui, Zhou Fang-Jian

Аннотация на английскомСтатьяОбзорПеревод пока не подготовлен

Аннотация

PURPOSE: To determine the predictive value and feasibility of the new outcome prediction model for Chinese patients with penile squamous cell carcinoma.

RESULTS

The 3-year disease-specific survival (DSS) survival (DSS) was 92.3% in patients with < 8.70 mg/L CRP and 54.9% in those with elevated CRP (P < 0.001). The 3-year DSS was 86.5% in patients with a BMI < 22.6 Kg/m2 and 69.9% in those with a higher BMI (P = 0.025). In a multivariate analysis, pathological T stage (P < 0.001), pathological N stage (P = 0.002), BMI (P = 0.002), and CRP (P = 0.004) were independent predictors of DSS. A new scoring model was developed, consisting of BMI, CRP, and tumor T and N classification. In our study, we found that the addition of the above-mentioned parameters significantly increased the predictive accuracy of the system of the American Joint Committee on Cancer (AJCC) anatomic stage group. The accuracy of the new prediction category was verified.

METHODS

A total of 172 Chinese patients with penile squamous cell cancer were analyzed retrospectively between November 2005 and November 2014. Statistical data analysis was conducted using the nonparametric method. Survival analysis was performed with the log-rank test and the Cox proportional hazard model. Based on regression estimates of significant parameters in multivariate analysis, a new BMI-, CRP- and pathologic factors-based scoring model was developed to predict disease--specific outcomes. The predictive accuracy of the model was evaluated using the internal and external validation.

CONCLUSIONS

The present study demonstrated that the TNCB score group system maybe a precise and easy to use tool for predicting outcomes in Chinese penile squamous cell carcinoma patients.

Для цитирования: Li Zai-Shang, Chen Peng, Yao Kai, Wang Bin, Li Jing, Mi Qi-Wu, Chen Xiao-Feng, Zhao Qi, Li Yong-Hong, Chen Jie-Ping, Deng Chuang-Zhong, Ye Yun-Lin, Zhong Ming-Zhu, Liu Zhuo-Wei, Qin Zi-Ke, Lin Xiang-Tian, Liang Wei-Cong, Han Hui, Zhou Fang-Jian. [Deep brain stimulation of the ventral intermediate thalamic nucleus in the treatment of essential tremor].. Neurologia i neurochirurgia polska. 2007. DOI: 10.18632/oncotarget.8037.

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