Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology · 2016
THE DIFFICULTIES OF DIFFERENTIAL DIAGNOSIS OF EDEMATOUS AND ANEMIC SYNDROMES IN AN EDERLY PATIENT WITH ATYPICAL COURSE OF COELIAC DISEASE.
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Viktorova I A, Grishechkina I A, Sobol L N, Polomoshnova T N
Аннотация
OBJECTIVE: Analysis of the complexities of diagnosis of atypical celiac disease in elderly patients.
KEY POINTS: A clinical observation of the patient 63 years with atypical form of celiac disease, have flowed mainly from edematous and anemic syndrome. High titers of antibodies to gliadin, tissue transglutaminase, histological changes of the mucous membrane of the small intestine (Marsh II), the presence DQA1*0501 of the alleles have confirmed diagnosis. Against the background of strict gluten-free diet and a half years I have come persistent clinical remission with normalization of serum indicators.
CONCLUSION: Inclusion in the plan of diagnostic screening for celiac disease in patients \'vith edematous and anemic syndrome possible to establish the correct diagnosis and to reduce the risk of complications (including malignancies) in this patient.
KEY POINTS: A clinical observation of the patient 63 years with atypical form of celiac disease, have flowed mainly from edematous and anemic syndrome. High titers of antibodies to gliadin, tissue transglutaminase, histological changes of the mucous membrane of the small intestine (Marsh II), the presence DQA1*0501 of the alleles have confirmed diagnosis. Against the background of strict gluten-free diet and a half years I have come persistent clinical remission with normalization of serum indicators.
CONCLUSION: Inclusion in the plan of diagnostic screening for celiac disease in patients \'vith edematous and anemic syndrome possible to establish the correct diagnosis and to reduce the risk of complications (including malignancies) in this patient.