Emerging infectious diseases · 2012
Autochthonous and dormant Cryptococcus gattii infections in Europe.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Hagen Ferry, Colom M Francisca, Swinne Daniëlle, Tintelnot Kathrin, Iatta Roberta, Montagna Maria Teresa, Torres-Rodriguez Josep M, Cogliati Massimo, Velegraki Aristea, Burggraaf Arjan, Kamermans Alwin, Sweere Johanna M, Meis Jacques F, Klaassen Corné H W, Boekhout Teun
Аннотация
Until recently, Cryptococcus gattii infections occurred mainly in tropical and subtropical climate zones. However, during the past decade, C. gattii infections in humans and animals in Europe have increased. To determine whether the infections in Europe were acquired from an autochthonous source or associated with travel, we used multilocus sequence typing to compare 100 isolates from Europe (57 from 40 human patients, 22 from the environment, and 21 from animals) with 191 isolates from around the world. Of the 57 human patient isolates, 47 (83%) were obtained since 1995. Among the 40 patients, 24 (60%) probably acquired the C. gattii infection outside Europe; the remaining 16 (40%) probably acquired the infection within Europe. Human patient isolates from Mediterranean Europe clustered into a distinct genotype with animal and environmental isolates. These results indicate that reactivation of dormant C. gattii infections can occur many years after the infectious agent was acquired elsewhere.