[Oral rehabilitation in Sotos syndrome: case report and scoping review of the literature].

Sotos syndrome (SS) is a rare genetic disorder characterized by overgrowth, distinctive facial features, and dentofacial abnormalities. While its oral manifestations are well documented in childhood, there is limited evidence regarding dental management in adults. This case report, prepared in accordance with the CARE guidelines, describes a 28-year-old woman diagnosed with SS who presented with typical craniofacial features of the condition. The patient sought care for partial edentulism, and oral rehabilitation with removable partial dentures was planned. The treatment approach considered the anatomical, functional, and cognitive limitations associated with the syndrome, and included a preventive phase, progressive prosthetic adaptation, and periodic clinical follow-ups. After four months, the patient showed satisfactory prosthetic adaptation, functional stability, and good oral hygiene. A scoping review of the literature was conducted following PRISMA-ScR guidelines. Searches were performed in the PubMed and Web of Science databases to identify studies reporting dental treatments in patients with a confirmed diagnosis of SS. Six case reports published between 2006 and 2023 were included. The most frequently reported oral manifestations were severe malocclusions, hypodontia, supernumerary teeth, and skeletal abnormalities. Management was interdisciplinary, with a focus on orthodontic therapies in younger patients and implant-supported rehabilitations in adults. Removable prosthetic rehabilitation represents a valid and effective alternative for adults with SS, particularly when implant-based treatments are contraindicated. This case contributes new clinical evidence and highlights the importance of personalized approaches and continuous follow-up in this patient population.