Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2025
The concept of virtual clinical trials: A game changer in radiation oncology research?
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Faivre-Finn Corinne, Baker Colin, Dempsey Clare, Fisher Jasmin, Frangi Alejandro F, Gosling Andrew, Hiley Crispin, Lowe Matthew, Marchant Tom, McWilliam Alan, Price Gareth, Rieu Romelie, van Herk Marcel, Vasquez Osorio Eliana, Woolf David, Aznar Marianne
Аннотация
Virtual clinical trials use computer simulations (e.g. radiation physics and radiobiology) and/or real-world data (e.g. patient anatomy and tissue characteristics) to model radiation oncology treatments, addressing limitations of traditional clinical trials. They aim to enhance subsequent trial design, improve patient selection, and reduce risk of unsuccessful trials. AI promises to boost their precision, enabling faster, more efficient research that keeps pace with evolving technologies and better reflects real-world clinical practice. Note: Many different terms are used in the literature to describe computer-simulated research approaches, including virtual clinical trials, simulated trials, and in silico trials. In this paper, we have chosen to use the term virtual clinical trials for consistency and clarity.