Acta gastro-enterologica Belgica · 2020
Enteropathy-associated T-cell Lymphoma (EATL) with intracranial metastasis : a rare and dismal condition.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Chuah Y Y, Tashi T, Lee Y Y, Fu T Y, Shih C A
Аннотация
BACKGROUND: Enteropathy-associated T-cell lymphoma (EATL) is a rare type of gastrointestinal non-Hodgkin's Lymphoma. EATL with intracranial metastasis is even rarer. We report a case of EATL with intracranial metastasis.
CASE PRESENTATION: A 36-years old man presented with five weeks history of intractable diarrhea. Colonoscopy was normal, but abdominal computed tomography (CT) scan revealed mural thickening at duodenojejunal junction, and subsequent jejunofiberoscopy showed a circumferential ulceration at the jejunum. Histo-immunopathology confirmed the diagnosis of enteropathyassociated T-cell lymphoma (EATL) type II. His disease course proved to be aggressive and refractory to standard front-line chemotherapy, and eventually progressed through second-line salvage regimen with CNS and intracranial involvement. He died nine months after the initial diagnosis.
CONCLUSION: EATL with brain metastasis is a very rare occurrence with dismal prognosis.
CASE PRESENTATION: A 36-years old man presented with five weeks history of intractable diarrhea. Colonoscopy was normal, but abdominal computed tomography (CT) scan revealed mural thickening at duodenojejunal junction, and subsequent jejunofiberoscopy showed a circumferential ulceration at the jejunum. Histo-immunopathology confirmed the diagnosis of enteropathyassociated T-cell lymphoma (EATL) type II. His disease course proved to be aggressive and refractory to standard front-line chemotherapy, and eventually progressed through second-line salvage regimen with CNS and intracranial involvement. He died nine months after the initial diagnosis.
CONCLUSION: EATL with brain metastasis is a very rare occurrence with dismal prognosis.