Malaria journal · 2017
An intricate case of multidrug resistant Plasmodium falciparum isolate imported from Cambodia.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Dell'Acqua Raffaele, Fabrizio Claudia, Di Gennaro Francesco, Lo Caputo Sergio, Saracino Annalisa, Menegon Michela, L'Episcopia Mariangela, Severini Carlo, Monno Laura, Castelli Francesco, Angarano Gioacchino
Аннотация
BACKGROUND: Imported cases of multidrug resistant Plasmodium falciparum and treatment failure with artemisinin-based regimens, although rare, have been described also in Western countries and their management is often challenging. This is also due to an inadequate knowledge and implementation of health prevention measures.
CASE REPORT: A complex case of imported malaria caused by Plasmodium vivax/P. falciparum isolates in a patient who was not taking chemoprophylaxis while he was travelling in Cambodia is reported in this article. After failures of artemisinin-based and both oral and intravenous quinine-based regimens, a multidrug resistant P. falciparum was detected. The patient was successfully treated with atovaquone-proguanil.
CONCLUSIONS: This experience highlights the importance of a careful management that should be based not only on the most up-to-date guidelines, but also on the awareness of a rapidly evolving scenario.
CASE REPORT: A complex case of imported malaria caused by Plasmodium vivax/P. falciparum isolates in a patient who was not taking chemoprophylaxis while he was travelling in Cambodia is reported in this article. After failures of artemisinin-based and both oral and intravenous quinine-based regimens, a multidrug resistant P. falciparum was detected. The patient was successfully treated with atovaquone-proguanil.
CONCLUSIONS: This experience highlights the importance of a careful management that should be based not only on the most up-to-date guidelines, but also on the awareness of a rapidly evolving scenario.