Acta ophthalmologica Scandinavica · 1999
Ultrasound biomicroscopical study of the irido-corneal angle in dominant juvenile open-angle glaucoma, in POAG, and in normal eyes.
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Urbak S F
Аннотация
PURPOSE: To compare various parameters of the chamber angle in a pedigree with dominant goniodysgenesis and juvenile open-angle glaucoma linked to chromosome 1q, GLC1A, with those in patients with adult-onset primary open-angle glaucoma, and in normal eyes.
METHODS: Ultrasound biomicroscopy was performed on 10 eyes with dominant goniodysgenesis and juvenile open-angle glaucoma, on 12 eyes with adult-onset primary open-angle glaucoma, and 24 normal eyes. Eight parameters were measured.
RESULTS: The anterior chamber angle, angle opening distance 500 microm from the scleral spur, trabecular meshwork--iris distance, and trabecular meshwork--iris pigment epithelium distance were statistically significantly higher in the group with juvenile glaucoma.
CONCLUSION: The wider chamber angle in dominant juvenile open-angle glaucoma could suggest a more complex anomaly with involvement of cornea and iris in addition to goniodysgenesis. The presence of goniodysgenesis in the dominant juvenile open-angle glaucoma patients could not be detected by ultrasound biomicroscopy, however.
METHODS: Ultrasound biomicroscopy was performed on 10 eyes with dominant goniodysgenesis and juvenile open-angle glaucoma, on 12 eyes with adult-onset primary open-angle glaucoma, and 24 normal eyes. Eight parameters were measured.
RESULTS: The anterior chamber angle, angle opening distance 500 microm from the scleral spur, trabecular meshwork--iris distance, and trabecular meshwork--iris pigment epithelium distance were statistically significantly higher in the group with juvenile glaucoma.
CONCLUSION: The wider chamber angle in dominant juvenile open-angle glaucoma could suggest a more complex anomaly with involvement of cornea and iris in addition to goniodysgenesis. The presence of goniodysgenesis in the dominant juvenile open-angle glaucoma patients could not be detected by ultrasound biomicroscopy, however.