Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2018
Validation of iScore and PLAN Score for Death in Thrombectomy in Acute Stroke Due to Anterior Circulation Large Artery Occlusion.
Сравнительное исследованиеСтатьяМногоцентровое исследованиеВалидационное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Chu Xiaopeng, Yang Yongxin, Zhang Fushan, Ye Ruidiong, Chu Wenzheng
Аннотация
BACKGROUND: To validate iScore and PLAN score in acute anterior circulation large vessel occlusion stroke patients undergoing thrombectomy.
METHODS: iScore and PLAN score were calculated for consecutive acute ischemic stroke undergoing thrombectomy were included and death at 1 month and death at 3 months were recorded. The area under the receiver operating characteristic curve was used to assess the discrimination ability of the scales for death.
RESULTS: Two hundred and twenty-nine patients were included, 25.3% (58 of 229) of patient died at 1 month after thrombectomy and 25.8% (59 of 229) of them died at 3 months after thrombectomy. The receiver operator curve analysis found that iScore (area under the curve [AUC] = .76, 95% confidence interval [CI] .69-.83) was numerically better than PLAN score (AUC = .73, 95% CI .66-.81) for predicting death at day 90. The cut-off for iScore is 193, with sensitivity 64%, specificity 79%, positive predictive value 75% and negative predictive value 69%.
CONCLUSIONS: The iScore scale is a valid predictive tool for death in anterior circulation large vessel occlusions undergoing thrombectomy.
METHODS: iScore and PLAN score were calculated for consecutive acute ischemic stroke undergoing thrombectomy were included and death at 1 month and death at 3 months were recorded. The area under the receiver operating characteristic curve was used to assess the discrimination ability of the scales for death.
RESULTS: Two hundred and twenty-nine patients were included, 25.3% (58 of 229) of patient died at 1 month after thrombectomy and 25.8% (59 of 229) of them died at 3 months after thrombectomy. The receiver operator curve analysis found that iScore (area under the curve [AUC] = .76, 95% confidence interval [CI] .69-.83) was numerically better than PLAN score (AUC = .73, 95% CI .66-.81) for predicting death at day 90. The cut-off for iScore is 193, with sensitivity 64%, specificity 79%, positive predictive value 75% and negative predictive value 69%.
CONCLUSIONS: The iScore scale is a valid predictive tool for death in anterior circulation large vessel occlusions undergoing thrombectomy.
Предметные рубрики MeSH
AgedArea Under CurveCerebrovascular CirculationChinaDecision Support TechniquesFemaleHumansInfarction, Middle Cerebral ArteryIntracranial ThrombosisMaleMiddle AgedPredictive Value of TestsROC CurveReproducibility of ResultsRetrospective StudiesRisk AssessmentRisk FactorsThrombectomyTime FactorsTreatment Outcome