BMJ open · 2025
Gender disparities in COVID-19 vaccine hesitancy in high-income countries: an umbrella review protocol.
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Wiedermann Christian J, Noviello Chiara, Palmieri Claudia, Stefanizzi Pasquale, Piccoliori Giuliano, Engl Adolf, Tafuri Silvio
Аннотация
INTRODUCTION: Vaccine hesitancy remains a critical public health challenge, especially in high-income countries. Gender differences in vaccine hesitancy can significantly affect vaccination rates and public health outcomes. The aim of this research is performing an umbrella review and meta-analysis to systematically investigate gender disparities in vaccine hesitancy for COVID-19 in high-income countries, as well as the quality, potential biases and dependability of epidemiological evidence.
METHODS AND ANALYSIS: The study will systematically search, extract and analyse data from reported systematic reviews and meta-analyses that focus specifically on gender differences in vaccine hesitancy. The search will include CINAHL, Cochrane Library, PubMed/MEDLINE, EMBASE and Epistemonikos for studies published from 2019 onward. The inclusion criteria will encompass systematic reviews and meta-analyses of non-interventional studies conducted in high-income countries. The identified factors contributing to vaccine hesitancy will be categorised based on demographic, psychological, social and economic dimensions. The methodological quality of the included meta-analyses will be assessed using the "Joanna Briggs Institute Critical Appraisal Checklist for Systematic Reviews and Research Syntheses" tool.
ETHICS AND DISSEMINATION: Ethical approval is not required for this umbrella review. These results will be published in a peer-reviewed journal.
PROSPERO REGISTRATION NUMBER: CRD42024572978.
METHODS AND ANALYSIS: The study will systematically search, extract and analyse data from reported systematic reviews and meta-analyses that focus specifically on gender differences in vaccine hesitancy. The search will include CINAHL, Cochrane Library, PubMed/MEDLINE, EMBASE and Epistemonikos for studies published from 2019 onward. The inclusion criteria will encompass systematic reviews and meta-analyses of non-interventional studies conducted in high-income countries. The identified factors contributing to vaccine hesitancy will be categorised based on demographic, psychological, social and economic dimensions. The methodological quality of the included meta-analyses will be assessed using the "Joanna Briggs Institute Critical Appraisal Checklist for Systematic Reviews and Research Syntheses" tool.
ETHICS AND DISSEMINATION: Ethical approval is not required for this umbrella review. These results will be published in a peer-reviewed journal.
PROSPERO REGISTRATION NUMBER: CRD42024572978.