[State of adrenergic innervation of rat mesentery and dura mater during immobilization stress].

Fluorescent microscopy combined with an assay of the intensity of nerve structure fluorescence was used to study adrenergic innervation of the rat mesentery and dura mater under immobilization stress. The adrenergic nerves were found to undergo morphofunctional changes over time. These changes were marked by a dramatic fall of noradrenaline fluorescence within the first immobilization hours, followed by rise at the 4th-6th hour of experiment. In prolonged immobilization, mediator activity of the adrenergic nerves remained under initial (control) level. The data obtained attest to the involvement of the peripheral adrenergic innervation in stressor response and in the adaptive mechanisms during immobilization.