[Detection of Helicobacter pylori in oral cavity of patients with recurrent aphthous ulcer].

OBJECTIVE

To investigate the association of recurrent aphthous ulcer (RAU) with Helicobacter pylori (Hp) infection and digestive diseases.

METHODS

Saliva samples were collected from 82 patients with RAU and 74 healthy volunteers for Hp detection with PCR.

RESULTS

The positivity rates of HP differed significantly between RAU patients and healthy volunteers (43.9% vs 16.2%, P<0.001). In the 82 RAU patients, 22 (26.82%) were identified to have gastritis and peptic ulcer, whereas only 7 out of the 74 healthy volunteers (10.45%) had such digestive diseases, showing significant difference between them (P<0.01).

CONCLUSION

Hp might in some way associate with RAU, which in turn is associated with an increased incidence of digestive diseases.