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BMC women's health · 2026

Relation between Helicobacter pylori infection and menopausal symptoms in diabetic women.

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Mohamed Nessren Mohamed Bahaa El Deen, Zidan Noura Ali Ghazy, Hussein Sara Mohammed Foaud, Altaweel Eman Hussein Soliman, Abdelmageed Neamat Abdelmageed, Mohamed Fatma Saffeyeldin, Ahmed Sally Abdelaziz, Yassien Marwa Abdelaziz Abo Saree, Abdelmaqsoud Doaa Mohamed Salama, Alkhawagah Sabah M, Elattar Shymaa M, Hassan Marwa M, Mohamed Moshira Ali Ibrahim

Аннотация

BACKGROUND AND AIM: Menopausal symptoms have marked negative impact on women’s physical and mental well-being and consumes substantial amount of health expenses. However, the relation between H. pylori infection and severity of menopausal symptoms is a scarcely discussed issue. The present cross-sectional study aims to explore the relation between H. pylori infection and severity of menopausal symptoms in diabetic women. SUBJECTS AND METHODS: The study included 150 postmenopausal diabetic women and 150 non-diabetic counterparts. H. pylori infection was assessed using a monoclonal enzyme immunoassay–based stool antigen test. Menopausal symptoms were evaluated using the Menopause Rating Scale (MRS). RESULTS: The present study included consecutive 150 diabetic and 150 non-diabetic postmenopausal women. Diabetic women had significantly higher frequency of severe menopausal symptoms (31.3% versus 14.0%, p<0.001) and significantly higher frequency of positive H. pylori infection (56.0% versus 40.7%, p = 0.011). Multivariate binary logistic regression analysis identified significant association between BMI [OR (95% CI): 1.09 (1.01–1.18), p = 0.022], hypertension [OR (95% CI): 3.97 (1.66–9.49), p = 0.002], HbA1c % [OR (95% CI): 1.18 (1.02–1.36), p = 0.029] and positive H. pylori infection [OR (95% CI): 4.09 (1.52-11.0), p = 0.005] and severe menopausal symptoms. CONCLUSIONS: Postmenopausal diabetic women had higher frequency of H. pylori infection which may be related to more severe menopausal symptoms in this population.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты