[An epidemiological study on the etiology of primary hepatocellular carcinoma in Guangzhou, Guangdong Province].

To assess the roles of suspected etiological factors in the pathogenic course of primary hepatocellular carcinoma (PHC) in Guangzhou city, a case control study including 100 cases and 100 controls were matched on sex, age, occupation, education degree of was carried out. The results from single factor analysis showed that factors as HBV infection, HCV infection, psychosocial factor, lack of separate kitchen and exhausting hood, habit of eating raw fish meat were related to PHC. Logistic regression analysis showed that HBV, HCV infection, psychic trauma, personality, separate kitchen, habit of eating raw fish meat might be regarded as risk factors for PHC in Guangzhou city. It is noticeable that a significant synergic effect was observed when some factors worked jointly.